Actualización Microscopios de Fluorescencia


Afordable and Powerful Super Resolution System

BioAxial has developed and patented a breakthrough super-resolution technology based on conical diffraction which is implemented in the CODIM100 instrument making possible the observation of live cells well below the current limit of 200-250 nanometers. This technology opens new possibilities for research scientists to make new discoveries, understand disease mechanisms and develop therapies to address several unresolved diseases such as cancer, Alzheimer, infections and more or develop new solutions in other life sciences applications. Read More



Real-Time Confocal System based on Dual-Disc Microlens Technology

The CSU-X1 is the advanced model of our CSU-series, which are widely recognized as the most powerful tools for live cell imaging. A Nipkow spinning disk containing about 20,000 pinholes and a second spinning disk containing the same number of microlens to focus excitation laser light into each corresponding pinhole are mechanically fixed with a motor, and very rapidly raster scan the field of view with about 1,000 laser beams when rotated. The pinhole and microlens pattern are arranged in our proprietary design to optimize raster scan. Multi-beam scanning with the CSU-X1 not only increases scanning speed, but also results in significantly lower photobleaching and phototoxicity, because multiple excitation needs only a low level of laser power at the specimen to fully excite fluorescence. Read More



Real-Time Confocal System based on Dual-Disc Microlens Technology

The CSU-W1 confocal scanner unit, a high-end model that follows the previously released CSU-X1, offers the superior performance and functionality that researchers require. With its significantly larger field of view, decreased crosstalk, and extended near-infrared spectral range, it can obtain sharper images of regions deeper inside live cells. Read More



Fluorescence Resonance Energy Transfer Imaging System

Förster (fluorescence) resonance energy transfer (FRET) is the process of radiation free energy transfer between two spatially close fluorophores called donor and acceptor. In FRET condition photoexcitation of the FRET-donor molecule leads to a decreased donor fluorescence and an induced fluorescence of the FRET acceptor.Read More



Total Internal Reflection Fluorescence Imaging System

The TIRF technique is a special kind of wide-field fluorescence microscopy for measuring cells or SMC in an evanescent field without haze. By total reflection of the exciting light (typical Laser) at the coverslip/medium-interface the fluorescence excitation is limited to a very thin space in vicinity of the glass surface. The resulting fluorescence images exhibit extremely high contrast and resolution with the possibility of realtime Imaging of cell membrane or labeled single molecules SMC. Read More



Fluorescence Recovery After Photobleaching Imaging System

All fluorescent dyes emit light of one wavelength after they have absorbed light of another wavelength. If a high intensity e.g. UV light illuminates the dyes, they react with photobleaching. The high intense light  renders the dyes unable to emit fluorescence. FRAP is working based on this phenomenon and is used typically to measure the dynamics of molecular mobility or movement of fluorescent labeled molecules. It is also possible to measure the exchange of molecules between separate compartments of the cells. Read More


VisiFRAP2D2D-VisiFRAP Realtime Scanner

Fluorescence Recovery After Photobleaching Imaging System

The 2D-VisiFRAP system from Visitron Systems GmbH is a microscope based imaging solution specially designed for fluorescence recovery or photoactivated studies. The system is based on a 2D galvanometer realtime scanner, a high sensitive CCD camera system, a research microscope like  Zeiss AxioObserver, Olympus BX/IX or Nikon E2000. Read More


FrapVisiScope Confocal FRAP

VisiScope Confocal with 2D-VisiFRAP Scanner

A compact and easy to handle system with simultaneous laser illumination for FRAP scanner and CSU confocal allows the simultaneous acquisition and display of confocal image with the FRAP bleaching as online overlay. No moving parts or optics are necessary because of a special optical design in the microscope. Read More


Cell ExplorerVisiScope Cell Explorer

The new challenge in Digital Fluorescence Microscopy: Multidimensional Acquisition and Analysis of living Cells

Modern cell biology on living cells and tissues has reached revolutionary success in biological, medical and pharmacological research in recent years. With the VisiScope system you can reliably document living organisms and intracellular processes, even over a period of several days. While someone has to work with none-automated microscopes resulting in restricted application possibilities in the past, nowadays fully automated fluorescence microscopes with multidimensional control have been established. The VisiScope Cell Explorer, based on Visitron imaging software, solves all these new challenges easily and user friendly with highest precision. Read More



High Speed Imaging System

This new generation of sCMOS imaging sensors is the first to combine all requirements for an ideal imaging device. Its 5,5 Mpixel array allows observation of large fields of view at maximum resolution (6,5 µm pixel size) and high speeds of up to 100 frames per second at an extremely low read noise level while still maintaining a high dynamic range of 24.000:1. Taken together, these features allow scientists to observe dynamic processes at unprecedented speed, resolution and sensitivity. Read More